Contrave (Naltrexone HCl / Bupropion HCl) Tablets

Take a clinically supported approach to sustained weight management with Contrave. Combining two established medications—naltrexone and bupropion—in an extended-release tablet, Contrave targets the areas of the brain that regulate appetite and reward, helping you reduce hunger, control powerful cravings, and stick to your reduced-calorie lifestyle plan.

Designed to be used alongside a balanced diet and regular physical activity, Contrave offers structured support for adults working to achieve long-term health goals.

Key Features & Benefits

• Dual-Action Brain Pathway Targeting: Works centrally on the hypothalamus (hunger center) and the mesolimbic dopamine circuit (reward system) to help curb appetite and quiet food cravings.

• Supports Lifestyle Changes: Acts as an aid to help bridge the gap, making it easier to manage portion control and adhere to a reduced-calorie meal plan.

• Convenient Oral Tablet: Taken as an oral tablet, avoiding the need for injections or complex medical device setups.

• Gradual Escalation Dosing: Follows a structured weekly titration schedule designed to help your body adjust comfortably and minimize common initial side effects.

Technical Specifications & Composition

• Active Ingredients: Naltrexone hydrochloride (8 mg) / Bupropion hydrochloride (90 mg) per extended-release tablet

• Drug Class: Opioid antagonist and aminoketone antidepressant combination

• Formulation: Extended-release oral tablets (must be swallowed whole; do not cut, crush, or chew)

• Standard Maintenance Dose: Typically two tablets taken twice daily (titrated upward over your first 4 weeks as directed by a physician)

• Indication: Prescribed for chronic weight management in adults with obesity or overweight who have at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol), used alongside diet and exercise.

What’s Included

• Prescription Medication Supply (Pack sizes vary based on prescription fill, typically provided in starter packs or 120-count monthly maintenance bottles)

• Patient Medication Guide & Instructions for Use

Important Safety & Prescription Notice:

Contrave is a prescription-only medication and is not safe for everyone. It must not be taken by individuals with uncontrolled high blood pressure, a history of seizures, eating disorders (such as anorexia or bulimia), those taking opioid medications or undergoing acute opioid withdrawal, or individuals taking MAO inhibitors. Because it contains bupropion, it carries a boxed warning regarding potential changes in mood or behavior. Always consult your healthcare provider to discuss your complete medical history before starting treatment.