Achieve steady, 24-hour blood sugar control with Tresiba®, a long-acting basal human insulin analog from Novo Nordisk. Engineered to provide an ultra-long duration of action, Tresiba delivers a flat, stable release profile that helps manage baseline glucose levels in adults and children (age 1 and older) with diabetes.
Why Choose Tresiba®?
Unlike traditional basal insulins, Tresiba forms a soluble multi-hexamer depot immediately after subcutaneous injection. This slow, continuous release ensures a consistent therapeutic effect with minimal peak fluctuations.
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Ultra-Long Duration: Provides reliable blood sugar control lasting beyond 42 hours, offering unmatched basal stability.
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Dosing Flexibility: Designed for once-daily dosing at any time of day. If a dose is missed, simply administer it as soon as remembered, ensuring at least 8 hours have elapsed between consecutive doses.
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Reduced Hypoglycemia Risk: Clinical profiles demonstrate a lower risk of nocturnal hypoglycemia compared to standard insulin glargine U-100.
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Two Concentration Strengths: Available in U-100 and high-potency U-200 to accommodate varying daily volume requirements without needing dose conversion math.
Understanding the Concentrations (U-100 vs. U-200)
Both strengths are delivered via the push-button FlexTouch® prefilled pen device. The dose window displays the exact number of units to be delivered—no dose calculation or conversion is necessary when switching strengths.
| Feature | Tresiba® U-100 | Tresiba® U-200 |
| Concentration | 100 units / mL | 200 units / mL (Double Density) |
| Delivery Options | 10 mL Vial & 3 mL FlexTouch® Pen | 3 mL FlexTouch® Pen Only |
| Max Single Injection | Up to 80 units per dose | Up to 160 units per dose |
| Dose Increments | Adjustable by 1-unit steps | Adjustable by 2-unit steps |
| Ideal For | Standard daily basal requirements | High-insulin-volume or insulin-resistant users |
Product Specifications & Storage
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Active Ingredient: Insulin degludec (rDNA origin).
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Route of Administration: Subcutaneous injection only (thigh, upper arm, or abdomen). Rotate injection sites daily.
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Unopened Storage: Refrigerate between 36°F–46°F (2°C–8°C) until the expiration date. Do not freeze or use if frozen.
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In-Use Storage: Keep at room temperature below 86°F (30°C) or in the refrigerator for up to 56 days (8 weeks).
Important Safety Notice: Prescription required. Tresiba is not for treating diabetic ketoacidosis (DKA). Never share insulin pens or needles between patients. Glucose levels must be monitored closely to avoid severe hypoglycemia.
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